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Man dies after ingesting chloroquine in an attempt to prevent coronavirus

chapjim

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This was not an approve drug for human consumption
Please read what this package was approve for?
Cleaning Fish Tanks

You are very definitely wrong about not being approved for human consumption.

I took Chloroquine (or Primaquine) off and on for years when I was traveling frequently to places where malaria is a threat. Both were prescribed by physicians,

It had a tendency to "clean my tanks" -- Primaquine less so than Chloroquine. I seem to have survived.
 

rickandcindy23

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How can you all be arguing about a drug that has been around since the year I was born, 1955, which has already been proven safe and is used for lupus and malaria? It's been proven safe for many decades, yet someone ingests fish tank cleaner, and everyone is saying this drug is unsafe.
 

klpca

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How can you all be arguing about a drug that has been around since the year I was born, 1955, which has already been proven safe and is used for lupus and malaria? It's been proven safe for many decades, yet someone ingests fish tank cleaner, and everyone is saying this drug is unsafe.
I think that it is unsafe for some. And ineffective for others. I had zero response to it, it is the perfect RA drug for my friend. Bodies are weird.

Anyway this is an academic discussion for us and a real life discussion for the doctors treating the patients.
 

WVBaker

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This was not an approve drug for human consumption.
Please read what this package was approve for?
Cleaning Fish Tanks

Chloroquine Phosphate is the one for fish.
 

dayooper

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I think that it is unsafe for some. And ineffective for others. I had zero response to it, it is the perfect RA drug for my friend. Bodies are weird.

Anyway this is an academic discussion for us and a real life discussion for the doctors treating the patients.

I think this is the key. It reacts differently to some than others. For some, it doesn’t have side effects, for some, they are mild and others life threatening. Same with effectiveness. For some it works and others not so much.
 

"Roger"

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How can you all be arguing about a drug that has been around since the year I was born, 1955, which has already been proven safe and is used for lupus and malaria? ...
At what dosage level? The level needed to treat coronovirus effectively (and that is far, far from certain), the dosage level might have to be much higher than anything it was approved. How safe is it then?
 

Talent312

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Just a bit cabin-feverish, I initially read the topic as...

-- "Man dies after ingesting chocolate." --
My first thought: At least he went in a state of bliss.
.
 
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WVBaker

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... That's also the one for humans.

FDA Letter to Stakeholders: Do Not Use Chloroquine Phosphate Intended for Fish as Treatment for COVID-19 in Humans
 

Synergy

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Last edited:

WVBaker

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They (rationally) think you should let medical professionals decide whether the potential benefits outweigh the risks of using it, and that they will use a pharmaceutical grade version.

Very much so however, feel free to choose your own poison. So to speak. ;)
 

MULTIZ321

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Small Chloroquine Study Halted Over Risk of Fatal
Heart Complications.


.


Richard
 

MULTIZ321

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More deaths, no benefit from malaria drug in VA virus study.


.


Richard
 

normab

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Every approved drug, whether Rx or OTC, has a safety and efficacy review prior to FDA approving it. Indeed, many clinical trials are stopped due to safety, which means undesirable side effects, I.e, death or other serious health problems. So not all drugs get through the completion of clinical trials. Drugs that have worked well but also have imperfect safety profiles may still be approved as FDA considers risk vs benefit. E.g.chemo drugs.

On the other hand, drugs that have lower efficacy, I.e. may only provide benefit to some patients can be approved if their safety profile is good. Claritin comes to mind. It does not work for everyone, by a long shot.

Another issue is dosing. Clinical studies also determine appropriate doses. And then there is the problem of drug interactions, sometimes one drug can make another more or less potent.

Unfortunately there were no large well controlled trials for this combination. But there are already safety profiles for both drugs and the ZPacks may have more safety issues than the hydochloroquine.

Just listen to the commercials for medications— they always list the major possible side effects at the end, it’s required by law.

I was hoping it would work, as both medicines are cheap and mostly available, but the proof will be in the data.
 

plpgma

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Well...It turns out that this man's wife is now being investigated for intentionally poisoning her husband and thereby possibly facing a manslaughter charge!

Detectives are investigating whether the man's wife, who is well known by those around her to be mentally unstable, decided on her own to administer some of the fish tank cleaner into her husband's drink (iced tea, I believe), without his consent or knowledge to prevent him from seeking medical attention for an injured leg. The man was apparently a well respected and former brilliant engineer -- someone who, according to his friends and associates, would never take it upon himself to ingest such a concoction.

Hmmm...I wonder whether we'll ever hear this side of the story on the major networks.
 

WVBaker

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Well...It turns out that this man's wife is now being investigated for intentionally poisoning her husband and thereby possibly facing a manslaughter charge!

Detectives are investigating whether the man's wife, who is well known by those around her to be mentally unstable, decided on her own to administer some of the fish tank cleaner into her husband's drink (iced tea, I believe), without his consent or knowledge to prevent him from seeking medical attention for an injured leg. The man was apparently a well respected and former brilliant engineer -- someone who, according to his friends and associates, would never take it upon himself to ingest such a concoction.

Hmmm...I wonder whether we'll ever hear this side of the story on the major networks.

"Don't waste your love on someone who doesn't deserve it"
William Shakespeare
 

DrQ

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Holy crap! I hope they did a thorough autopsy on the guy.

"A friend of Lenius's said that ... "often made a cocktail of vitamins for Gary."​
Those who knew Gary said he was in "good spirits" and seemed "normal" in the days before he died. One source said that Gary had recently started undergoing chelation therapy, a medical procedure that is typically used to treat people who have abnormally high levels of heavy metals in their blood, such as lead, mercury, or arsenic. It is sometimes also used as a homeopathic remedy for heart disease, autism, and Alzheimer's disease."​

After reading the article, I wouldn't ingest anything offered from that woman.
 

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It looks like you missed the other recent news blowup about this topic ;-)

And, as something of a devil's advocate : doctors can totally prescribe this (any?) medication off-label if in their educated judgement the benefits outweigh the risks. I'm just not certain I am clear on who did the weighing in this instance, or where they got their estimation of benefit, or even if I'm convinced that the risk was minimal in the specific case I'm discussing oh-so-vaguely...
 

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Panina

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As with most studies, this is a subset of severity of the illness, hospitalization. I would like to see one with at the beginning of your symptoms, not needing to be hospitalized and immediately took it and the results.
 

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Another "no confidence" opinion:


"Interpretation
We were unable to confirm a benefit of hydroxychloroquine or chloroquine, when used alone or with a macrolide, on in-hospital outcomes for COVID-19. Each of these drug regimens was associated with decreased in-hospital survival and an increased frequency of ventricular arrhythmias when used for treatment of COVID-19."​
 

MULTIZ321

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