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Man dies after ingesting chloroquine in an attempt to prevent coronavirus

pedro47 said:
This was not an approve drug for human consumption
Please read what this package was approve for?
Cleaning Fish Tanks
Click to expand...

You are very definitely wrong about not being approved for human consumption.

I took Chloroquine (or Primaquine) off and on for years when I was traveling frequently to places where malaria is a threat. Both were prescribed by physicians,

It had a tendency to "clean my tanks" -- Primaquine less so than Chloroquine. I seem to have survived.
 
How can you all be arguing about a drug that has been around since the year I was born, 1955, which has already been proven safe and is used for lupus and malaria? It's been proven safe for many decades, yet someone ingests fish tank cleaner, and everyone is saying this drug is unsafe.
 
rickandcindy23 said:
How can you all be arguing about a drug that has been around since the year I was born, 1955, which has already been proven safe and is used for lupus and malaria? It's been proven safe for many decades, yet someone ingests fish tank cleaner, and everyone is saying this drug is unsafe.
Click to expand...
I think that it is unsafe for some. And ineffective for others. I had zero response to it, it is the perfect RA drug for my friend. Bodies are weird.

Anyway this is an academic discussion for us and a real life discussion for the doctors treating the patients.
 
pedro47 said:
This was not an approve drug for human consumption.
Please read what this package was approve for?
Cleaning Fish Tanks
Click to expand...

Chloroquine Phosphate is the one for fish.
 
klpca said:
I think that it is unsafe for some. And ineffective for others. I had zero response to it, it is the perfect RA drug for my friend. Bodies are weird.

Anyway this is an academic discussion for us and a real life discussion for the doctors treating the patients.
Click to expand...

I think this is the key. It reacts differently to some than others. For some, it doesn’t have side effects, for some, they are mild and others life threatening. Same with effectiveness. For some it works and others not so much.
 
rickandcindy23 said:
How can you all be arguing about a drug that has been around since the year I was born, 1955, which has already been proven safe and is used for lupus and malaria? ...
Click to expand...
At what dosage level? The level needed to treat coronovirus effectively (and that is far, far from certain), the dosage level might have to be much higher than anything it was approved. How safe is it then?
 
Just a bit cabin-feverish, I initially read the topic as...

-- "Man dies after ingesting chocolate." --
My first thought: At least he went in a state of bliss.
.
 
Last edited:
Synergy said:
... That's also the one for humans.
Click to expand...

FDA Letter to Stakeholders: Do Not Use Chloroquine Phosphate Intended for Fish as Treatment for COVID-19 in Humans
www.fda.gov

Fish Chloroquine Is Not for Human Use

Chloroquine products sold for aquarium use have not been evaluated by the FDA and should not be taken by humans to treat novel coronavirus (COVID-19).
www.fda.gov www.fda.gov
 
Synergy said:
They (rationally) think you should let medical professionals decide whether the potential benefits outweigh the risks of using it, and that they will use a pharmaceutical grade version.
Click to expand...

Very much so however, feel free to choose your own poison. So to speak. ;)
 
Small Chloroquine Study Halted Over Risk of Fatal
Heart Complications.


www.nytimes.com

Small Chloroquine Study Halted Over Risk of Fatal Heart Complications

A research trial of coronavirus patients in Brazil ended after patients taking a higher dose of chloroquine, one of the drugs President Trump has promoted, developed irregular heart rates.
www.nytimes.com www.nytimes.com
.


Richard
 
More deaths, no benefit from malaria drug in VA virus study.


apnews.com

More deaths, no benefit from malaria drug in VA virus study

A malaria drug widely touted by President Donald Trump for treating the new coronavirus showed no benefit in a large analysis of its use in U.S. veterans hospitals. There were more deaths among...
apnews.com apnews.com
.


Richard
 
Every approved drug, whether Rx or OTC, has a safety and efficacy review prior to FDA approving it. Indeed, many clinical trials are stopped due to safety, which means undesirable side effects, I.e, death or other serious health problems. So not all drugs get through the completion of clinical trials. Drugs that have worked well but also have imperfect safety profiles may still be approved as FDA considers risk vs benefit. E.g.chemo drugs.

On the other hand, drugs that have lower efficacy, I.e. may only provide benefit to some patients can be approved if their safety profile is good. Claritin comes to mind. It does not work for everyone, by a long shot.

Another issue is dosing. Clinical studies also determine appropriate doses. And then there is the problem of drug interactions, sometimes one drug can make another more or less potent.

Unfortunately there were no large well controlled trials for this combination. But there are already safety profiles for both drugs and the ZPacks may have more safety issues than the hydochloroquine.

Just listen to the commercials for medications— they always list the major possible side effects at the end, it’s required by law.

I was hoping it would work, as both medicines are cheap and mostly available, but the proof will be in the data.
 
Well...It turns out that this man's wife is now being investigated for intentionally poisoning her husband and thereby possibly facing a manslaughter charge!

Detectives are investigating whether the man's wife, who is well known by those around her to be mentally unstable, decided on her own to administer some of the fish tank cleaner into her husband's drink (iced tea, I believe), without his consent or knowledge to prevent him from seeking medical attention for an injured leg. The man was apparently a well respected and former brilliant engineer -- someone who, according to his friends and associates, would never take it upon himself to ingest such a concoction.

Hmmm...I wonder whether we'll ever hear this side of the story on the major networks.
 
plpgma said:
Well...It turns out that this man's wife is now being investigated for intentionally poisoning her husband and thereby possibly facing a manslaughter charge!

Detectives are investigating whether the man's wife, who is well known by those around her to be mentally unstable, decided on her own to administer some of the fish tank cleaner into her husband's drink (iced tea, I believe), without his consent or knowledge to prevent him from seeking medical attention for an injured leg. The man was apparently a well respected and former brilliant engineer -- someone who, according to his friends and associates, would never take it upon himself to ingest such a concoction.

Hmmm...I wonder whether we'll ever hear this side of the story on the major networks.
Click to expand...

"Don't waste your love on someone who doesn't deserve it"
William Shakespeare
 
Holy crap! I hope they did a thorough autopsy on the guy.

"A friend of Lenius's said that ... "often made a cocktail of vitamins for Gary."​
​
Those who knew Gary said he was in "good spirits" and seemed "normal" in the days before he died. One source said that Gary had recently started undergoing chelation therapy, a medical procedure that is typically used to treat people who have abnormally high levels of heavy metals in their blood, such as lead, mercury, or arsenic. It is sometimes also used as a homeopathic remedy for heart disease, autism, and Alzheimer's disease."​

After reading the article, I wouldn't ingest anything offered from that woman.
 
It looks like you missed the other recent news blowup about this topic ;-)

And, as something of a devil's advocate : doctors can totally prescribe this (any?) medication off-label if in their educated judgement the benefits outweigh the risks. I'm just not certain I am clear on who did the weighing in this instance, or where they got their estimation of benefit, or even if I'm convinced that the risk was minimal in the specific case I'm discussing oh-so-vaguely...
 
As with most studies, this is a subset of severity of the illness, hospitalization. I would like to see one with at the beginning of your symptoms, not needing to be hospitalized and immediately took it and the results.
 
Another "no confidence" opinion:


"Interpretation​
We were unable to confirm a benefit of hydroxychloroquine or chloroquine, when used alone or with a macrolide, on in-hospital outcomes for COVID-19. Each of these drug regimens was associated with decreased in-hospital survival and an increased frequency of ventricular arrhythmias when used for treatment of COVID-19."​
 
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