We usually travel with kids
We're from the upstate in SC so I'm interested to hear what others might have to add.
We are beach / water lovers so our favorite list will almost always include the ocean or great pools. Our "kids" range from 0-35 w/grandkids.
We love the coastal SC barrier islands from Hilton Head to Wild Dunes. We prefer gated communities and spent Easter at Seabrook with 6 kids 3-17 - we did LOTS of bike riding, playing on the beach and swimming/splashing in the pool area (as you know we had great warm weather this Easter).
We have a house rented in Sea Pines next month when the grandkids come. We did this last year in Palmetto Dunes and they've all begged for a repeat (we don't actually like Myrtle Beach. (personal preference)..except the Marriott there is wonderful....but with 8 kids it's a bit too much).
If you're looking for waterpark fun at a timeshare I've been wanting to check out that Wyndham in Severville(sp)....it sounds like the Great Wolf Lodge we visited last year outside of Charlotte - the boys (10&11 especially loved the GWL....waterslides & MAGIQUEST) it was a great hit.
There are wonderful waterpark resorts in Orlando (check out Harbour Lakes or Reunion resort - LOVED THEM both)....The Reunion resort got us to checking out the one near St Augustine as well on Hammock Beach - WONDERFUL! Beautiful resort on the ocean with a waterpark type pool area.
Took the boys to Washington with a stop in Jamestown/Yorktown area - Loved that trip too...(new museums there are great!)...one of our few trips without water. We went in April (after spring break), weather & lack of crowds were wonderful!
Since you're also from SC.....feel free to PM me and share your own ideas....I have tons.
So much to see and do

......not enough time or money
