Hi,
Lakeshore reserve is the newest Marriott in Orlando and right next to the Ritz and the JW Marriott which have good restaurants and spa. It would be good for adults but I'm not sure that the views from the rooms are all that great.
We love Cypress Harbour and it has a large adult following. It is good for families with kids too but it is a bit quieter than say Grande Vista and harbour Lake that have tons and tons of kids.
We have also stayed at Sabal palms and it has less kids but almost no activities. You do have access to the marriott world center with restaurants and great pools
I liked Cypress Harbour with its tea and cookies (adults only) most mornings where you could meet other adults and enjoy some great conversations.