Preliminary data of Possible Covid 19 treatments or vaccines

[BJRSanDiego]

I recently had shot #2 for the shingles vaccine. The paperwork said that I had a 60% chance that I wouldn't be able to continue my usual activities for a few day due to fever, chills, aches and pains, sore arm, head ache, low energy, etc. I ended up with a fever, low energy, aches and pains. But after a day or two things improved.

So when I see that a much lower percentage of Covid vaccine side effects, that doesn't displease me.

 

[MULTIZ321]

I Felt Fine, But Tested Positive For The Coronavirus. What's That Really Mean?

I Felt Fine, But Tested Positive For The Coronavirus. What's That Really Mean?

Science writer Robin Marantz Henig has written about dangerous emerging pathogens for 30 years. But none of what she learned could shed light on her own confusing encounter with this virus.

www.npr.org

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Richard

 

[MULTIZ321]

Here's where all the COVID-19 vaccine candidates currently stand.

Here’s where all the COVID-19 vaccine candidates currently stand

Here are some of the strongest vaccine candidates for COVID-19 that have either been approved for limited use or have entered clinical trials.

www.popsci.com

Richard

 

[MULTIZ321]

Johnson & Johnson Takes Big Step Forward With lts Vaccine Trial, has Potential to Be Single Shot.

Johnson & Johnson Takes Big Step Forward With Its Vaccine Trial, Has Potential to Be Single Shot

Two COVID-19 vaccines have now been approved for emergency use by the U.S. Food and Drug Administration as the nation continues to see record numbers of coronavirus cases. In the midst of all the news from Pfizer and Moderna, though, another company has announced it made progress in its own...

www.nbcboston.com

Richard

 

[MULTIZ321]

Russia to Jointly Produce Sputnik V COVID-19 Vaccine With India.

Russia to Jointly Produce Sputnik V COVID-19 Vaccine With India

This announcement comes at a time when the India has announced that vaccination drive is likely to start in January.

www.thequint.com

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Richard

 

[MULTIZ321]

Bharat Biotech s Covaxin shows encouraging results in clinical trials:Research paper.

Bharat Biotech's Covaxin shows encouraging results in clinical trials: Research paper

Business News: Get the latest Business News, Live Share & Stock Market Updates, Top News from India and across world. Read Top Business News and updates on financial, economic and banking news on CNBCTV18.

www.cnbctv18.com

Richard

 

[MULTIZ321]

What could happen if people skip the second dose of the COVID vaccine.

What could happen if people skip the second dose of the COVID vaccine

One out of four patients missed a dose of a two-dose shingles vaccine. That could spell trouble.

fortune.com

Richard

 

[MULTIZ321]

Why you still need to wear a mask after getting COVID -19 vaccine.

Why you still need to wear a mask after getting COVID-19 vaccine

Getting the vaccine does not mean you can ignore precautions.

abcnews.go.com

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Richard

 

[MULTIZ321]

Analysis of patient data reveals most common complications of COVID-19.

Analysis of patient data reveals most common complications of COVID-19

By looking at patient data, experts have confirmed that some of the most common complications of COVID-19 include pneumonia, kidney failure, and sepsis.

www.medicalnewstoday.com

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Richard

 

[MULTIZ321]

New studies indicate immunity to virus lasts at least 6-8 months after recovery.

New studies indicate immunity to virus lasts at least 6-8 months after recovery

One paper shows body retains high level of memory B cells for lengthy period; two others indicate reinfection chances very low for at least half a year

www.timesofisrael.com

Richard

 

[MULTIZ321]

Ten reasons why we got Covid-19 vaccines so quickly without 'cutting corners'

Ten reasons why we got Covid-19 vaccines so quickly without 'cutting corners' | Adam Finn

There’s been a compromise on standards, but it’s down to a combination of foresight, hard work and lucky breaks, says Prof Adam Finn

www.theguardian.com

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Richard

 

[PcflEZFlng]

Ten reasons why we got Covid-19 vaccines so quickly without 'cutting corners'

Ten reasons why we got Covid-19 vaccines so quickly without 'cutting corners' | Adam Finn

There’s been a compromise on standards, but it’s down to a combination of foresight, hard work and lucky breaks, says Prof Adam Finn

www.theguardian.com

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Richard

Great article and summary. Thank you Richard.

 

[Ralph Sir Edward]

Ten reasons why we got Covid-19 vaccines so quickly without 'cutting corners'

Ten reasons why we got Covid-19 vaccines so quickly without 'cutting corners' | Adam Finn

There’s been a compromise on standards, but it’s down to a combination of foresight, hard work and lucky breaks, says Prof Adam Finn

www.theguardian.com

.


Richard

I have to disagree with the "without cutting corners". Corners were cut, but the cut corners weren't mentioned in the article. Examples:

No testing was listed for being able to transmit (or not being able to transmit) the virus, even if protected by the vaccine. That's the difference between "stamping out" an epidemic and letting it smoulder, pretty much unseen.

Totally new vaccine type was used, that has no evidence of long term effects, good, bad or indfferent. You can't look at other vaccine types, each mechanism can and will have different long term effects.

No knowledge of how long the vaccine protects.

No testing for what happens when a vaccinated person gets a different covid infection. Cross reactions, no cross reactions, severe immune response, ect.

I could go on, but I am not popular on this, as it is already. . .

 

[x3 skier]

I have to disagree with the "without cutting corners". Corners were cut, but the cut corners weren't mentioned in the article. Examples:

No testing was listed for being able to transmit (or not being able to transmit) the virus, even if protected by the vaccine. That's the difference between "stamping out" an epidemic and letting it smoulder, pretty much unseen.

Totally new vaccine type was used, that has no evidence of long term effects, good, bad or indfferent. You can't look at other vaccine types, each mechanism can and will have different long term effects.

No knowledge of how long the vaccine protects.

No testing for what happens when a vaccinated person gets a different covid infection. Cross reactions, no cross reactions, severe immune response, ect.

I could go on, but I am not popular on this, as it is already. . .

Are you going to get vaccinated against COVID-19?

Cheers

 

[Ralph Sir Edward]

Maybe, maybe not. I am waiting on the J&J results. It is much more of an "old school" vaccine. I will re-evaluate the m-RNA vaccines this summer. Until then, I'm staying in lock-down.

Laugh all you want. . . .

 

[x3 skier]

Maybe, maybe not. I am waiting on the J&J results. It is much more of an "old school" vaccine. I will re-evaluate the m-RNA vaccines this summer. Until then, I'm staying in lock-down.

Laugh all you want. . . .

Not laughing, just curious. Everyone has different risk assessments.

Cheers

 

[Ralph Sir Edward]

Not laughing, just curious. Everyone has different risk assessments.

Cheers

I guess it depends on your knowledge base. When I picked up my Micro/Molecular biology degree, all the profs included a research history of their specialties. In virology, teh prof had been on the Sabin development team, and talked about both the science and the politics behind the Polio vaccines. (She had BEEN there). The SV40 fiasco. Another prof explains how a researcher had gotten a Nobel Prize with a Waring blender (true!). The point of all the profs was to "rap the student's teeth" in the fact that you had to "think outside the box" on everything in Microbiology.

Maybe I learned the lessons too well. . .

And I first heard what was to become know as AIDS in 1977. . . . .

 

[MULTIZ321]

Why Do the COVID-19 Vaccines Need to Be Stored in Frigid Temperatures? A Doctor Explains.

A Doctor Explains Why the COVID-19 Vaccines Have to Be Stored in Frigid Temperatures

Plus, what that means for a nationwide distribution plan.

www.prevention.com

Richard

 

[skimeup]

There are some credible studies now that strongly suggest that the MMR vaccine "primes" the immune system to fight against COVID. In this paper:

Analysis of Measles-Mumps-Rubella (MMR) Titers of Recovered COVID-19 Patients | mBio

COVID-19 has presented various paradoxes that, if understood better, may provide clues to controlling the pandemic, even before a COVID-19 vaccine is widely available. First, young children are largely spared from severe disease. Second, numerous ...

mbio.asm.org

the researchers indicate that the protection provided from the MMR vaccine is likely coming from the mumps portion, as the severity of symptoms was inversely proportional to the amount of mumps titer in the body. They looked at a selection of known (through lab tests) COVID survivors and selected those young enough to have received the MMRII (second gen) vaccine that was given starting in 1979. Compared them with folks over 57 who had received basically no MMR vaccine and found striking differences. (It didn't come into play in combination until 1971). Like the TB vaccine, they lean towards thinking that this could explain why the disease is far more devastating in the older population than the younger.

When I thought about it, it made sense to me to get that vaccine for two reasons. One - the possibility that this could confer some immunity while I (at 77) wait for the COVID vaccine to come my way. Secondly, I live in California where there is an active anti-vaxxer movement and thus kids now getting infected with measles who could pass that along to me. Protection against measles is a pretty sure thing. Protection against COVID is a strong possibility. We'll see....

 

[Monykalyn]

There are some credible studies now that strongly suggest that the MMR vaccine "primes" the immune system to fight against COVID. In this paper:

Analysis of Measles-Mumps-Rubella (MMR) Titers of Recovered COVID-19 Patients | mBio

COVID-19 has presented various paradoxes that, if understood better, may provide clues to controlling the pandemic, even before a COVID-19 vaccine is widely available. First, young children are largely spared from severe disease. Second, numerous ...

mbio.asm.org

the researchers indicate that the protection provided from the MMR vaccine is likely coming from the mumps portion, as the severity of symptoms was inversely proportional to the amount of mumps titer in the body. They looked at a selection of known (through lab tests) COVID survivors and selected those young enough to have received the MMRII (second gen) vaccine that was given starting in 1979. Compared them with folks over 57 who had received basically no MMR vaccine and found striking differences. (It didn't come into play in combination until 1971). Like the TB vaccine, they lean towards thinking that this could explain why the disease is far more devastating in the older population than the younger.

When I thought about it, it made sense to me to get that vaccine for two reasons. One - the possibility that this could confer some immunity while I (at 77) wait for the COVID vaccine to come my way. Secondly, I live in California where there is an active anti-vaxxer movement and thus kids now getting infected with measles who could pass that along to me. Protection against measles is a pretty sure thing. Protection against COVID is a strong possibility. We'll see....

That is really interesting! I had titers checked with first pregnancy 20+ years ago-had to get the rubella part 2 x to get those titers up.
It is interesting finds like this that could have really really helped slow covid spread-while MMR vax isn't risk free (but what is?) it may have helped our nursing home population to survive by innoculating with MMR vax. We desperately need a formal way to share knowledge across systems for medical professionals to have faster access. It also makes me wonder if there is a way to look back on those who are younger but had severe disease/died from covid to see if they were fully vaccinated.
If I didn't know I had good titers (and definitely if living in CA right now) I'd think I'd probably be getting the MMR vax too!!

 

[Ralph Sir Edward]

The Oxford adenovirus based vaccine was approved in the UK. Estimated 100 million doses in the first quarter for the UK. We'll see how effective it actually is. (Dodgy testing protocol. . . )

 

[Ralph Sir Edward]

The NIH has removed their restriction on the use of Ivermectin for COVID-19.

https://covid19criticalcare.com/