Preliminary data of Possible Covid 19 treatments or vaccines

[Panina]

COVID-19 treatment shows 100% survival rate - preliminary data

Not only have all the patients survived, according to Pluristem, but four of them showed improvement in respiratory parameters.

www.jpost.com

 

[Panina]

Coronavirus: Novavax to start human trial for vaccine

Novavax said preliminary immunogenicity and safety results from the trial were expected in July.

www.jpost.com

 

[klpca]

COVID-19 treatment shows 100% survival rate - preliminary data

Not only have all the patients survived, according to Pluristem, but four of them showed improvement in respiratory parameters.

www.jpost.com

Obviously a very small data set, but great to see the positive results. I saw that the treatment is also showing signs of being helpful for those with pulmonary hypertension, which I had never heard of until my Aunt was diagnosed with it in February and was given a grim prognosis. There was limited treatment available and nothing is worse than discovering a loved one is ill with a nearly untreatable illness. I love seeing what treatments that the researchers are developing. I hope that this proves to be successful. Thanks for posting.

 

[Panina]

Doctor gambles on clot-busting drug to save virus patients

WASHINGTON (AP) — The woman was dying. New York’s Mount Sinai Hospital was about to call her husband and break the news that there was nothing left to try...

apnews.com

 

[easyrider]

COVID-19 treatment shows 100% survival rate - preliminary data

Not only have all the patients survived, according to Pluristem, but four of them showed improvement in respiratory parameters.

www.jpost.com

I wonder if the PLX cells they get from placentas and used as a treatment are a stem cell ? 100% survival rate is hard to beat, imo.

Bill

 

[Panina]

29-year-old COVID-19 patient treated with Israel's new ‘passive vaccine’

Hospital says young man is in serious but stable condition

www.jpost.com

 

[Panina]

Reasons for hope: the drugs, tests and tactics that may conquer coronavirus

With much of the world living in lockdown, the spread of the new coronavirus, SARS-CoV-2, that was first detected in China late last year is beginning to slow in some places. As of April 12, 1.8 million had been infected and 115,000 killed by COVID-19, the disease caused...

www.reuters.com

 

[pedro47]

Thank Panina for sharing this information.

 

["Roger"]

Link

From the report in the link: Brazil had to suspend a trial of hydroxychloroquine after too many participants were developing heart arrhythmia.

So much for the link, now: I am not a doctor or a research scientist, so don't put too much faith in what I say below. It is a layman's comment and not that of a qualified expert.

From what I read, it seemed that even in the "successful" reports of hydroxychloroquine, it only helped those with mild symptoms and then speeded their recovery. (A later Chinese report suggested that it might not have any effect.) It could well have been that the Brazilian team was trying higher dosages (they had been doing that) in an attempt to see if the drug would then have a more successful impact with an increased dosage. Heart problems were a rare, but known side effect of lower dosages. The higher dosages might just have increased the frequency of that side effect. (Again, this is a layperson's speculation.)

 

[Panina]

UK Biobank: DNA to unlock coronavirus secrets

A vast store of DNA is being used to study why the severity of symptoms for coronavirus is so varied.

 

["Roger"]

This is a last gasp, measure. Hopefully none of us will get to the point that we would need this treatment.

extracorporeal membrane oxygenation (ECMO) therapy

Note: I find is scary that they had already tried most of the other experimental treatments: "...Enes Dedic was treated with all the potential drugs used for COVID-19 including hydrochloroquine, azithromycin, Kaletra, Actemra, antibiotics and anti-inflammatories."

 

[Panina]

Coronavirus treatment initially successful with first two patients

Opanagib is a "new chemical entity" which is administered orally and performs "anticancer, anti-viral and anti-inflammatory activities."

www.jpost.com

 

[Panina]

The experimental COVID-19 treatment remdesivir is showing promise in a Chicago clinical trial, according to the health news site STAT.
https://www.foxnews.com/science/experimental-coronavirus-drug-remdesivir-chicago-trial-shows-promise

 

["Roger"]

Here is a positive report on early trials of Remdesivir

 

[Ralph Sir Edward]

I read elsewhere that remdesvir had 25% serious side effects in the trial.

 

[Ralph Sir Edward]

Link

From the report in the link: Brazil had to suspend a trial of hydroxychloroquine after too many participants were developing heart arrhythmia.

So much for the link, now: I am not a doctor or a research scientist, so don't put too much faith in what I say below. It is a layman's comment and not that of a qualified expert.

From what I read, it seemed that even in the "successful" reports of hydroxychloroquine, it only helped those with mild symptoms and then speeded their recovery. (A later Chinese report suggested that it might not have any effect.) It could well have been that the Brazilian team was trying higher dosages (they had been doing that) in an attempt to see if the drug would then have a more successful impact with an increased dosage. Heart problems were a rare, but known side effect of lower dosages. The higher dosages might just have increased the frequency of that side effect. (Again, this is a layperson's speculation.)

Roger, hydroxycholoquine acts as a zinc channeling drug into cells. The zinc tends to interrupt a part of viral replication. It would work best with additional zinc suppliment, which is ofter omitted in these trials. Yes, it is an early stage treatment only. Once you get to the cytokinase storm stage, it would do very little good. (Some researchers think it affect the COVID attack on hemoglobin, but this is "up in the air". It does this against malaria, part of its anti malarial effectiveness.)

We are still learning about how the virus attacks the body.

 

[Rolltydr]

Hydroxychloroquine is linked to higher rates of death in VA coronavirus patients, study says.

https://www.washingtonpost.com/business/2020/04/21/anti-malarial-drug-trump-touted-is-linked-higher-rates-death-va-coronavirus-patients-study-says/

 

[Panina]

Possible coronavirus vaccine enters human testing trial

Progress is being made towards a viable vaccine for the coronavirus say researchers at a Philadelphia-based pharmaceutical company. Inovio Pharmaceuticals along with the University of Pennsylvania’s research facility, the Wistar Institute have been working on the vaccine as early as this past...

www.foxnews.com

 

[dayooper]

This is from The University of Louisville

https://www.uoflnews.com/section/sc...ogy-shows-promise-fighting-novel-coronavirus/

 

[Brett]

Hydroxychloroquine is linked to higher rates of death in VA coronavirus patients, study says.

https://www.washingtonpost.com/business/2020/04/21/anti-malarial-drug-trump-touted-is-linked-higher-rates-death-va-coronavirus-patients-study-says/

seems like the hyping of hydroxychloroquine as a virus cure is decreasing

 

[Bill4728]

Regarding the Covid 19 antibody test studies. (Like the Stanford study in the Bay area or the new NYC study)


These studies seem to show that there is a huge amount of under-counting of people who have been infected (10x-80x) that means instead of < 1% of the "hard hit cities" populations having had Covid That maybe 10-20% of the areas may have had Covid.

PLUS having worked in a medical laboratory for 30+ years testing for IgG antibodies is possible as early as ten days after resolving the disease BUT many / most people will not be positive for 4-8 weeks. So if these antibody studies are finding 20% positives in people who may have had the disease in the past few weeks, the positive rate could be a lot higher in a couple more weeks.

What does this mean? It means that if 20-40 % of the population in these areas have already had Covid then they don't need to social distance themselves and very very likely can't give this to anyone else.

BUT in areas where Covid is still rare, social distancing is still a great idea.

 

[Panina]

Coronavirus: First patients injected in UK vaccine trial https://www.bbc.co.uk/news/health-52394485

 

[MULTIZ321]

The FDA just approved Columbia's Covid-19 plasma
therapy study, backed by Amazon.

The FDA just approved Columbia's Covid-19 plasma therapy study, backed by Amazon

Amazon backed a study at Columbia University to help determine if it's safe and effective to give plasma collected from those who have recovered from the Covid-19 virus to other severely ill patients.

www.cnbc.com

.


Richard

 

[PigsDad]

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[easyrider]

[Let's give the snide political comments a rest, shall we?]

I think they were talking about FDA approved antiseptics, germicides and ultraviolent light. Even so, I bet there is a run on Lysol,lol.

Bill

Could a New Ultraviolet Technology Fight the Spread of Coronavirus?

Columbia researcher David Brenner believes far-UVC light—safe for humans, but lethal for viruses—could be a ‘game changer.’

news.columbia.edu

List of Antiseptic and germicides - Drugs.com

Compare antiseptic and germicides. View important safety information, ratings, user reviews, popularity and more.

www.drugs.com