It depends on the resort. Some resorts have only 2BR L/O and you can lockoff at anytime although many agents have to get a supervisor to help do it. If the resort has both 2BR and 2BR L/O you may be unable to lockoff a dedicated 2BR when there are no more available 2 BR L/O units when you want it done. The agent will be able to tell you if it is possible or not.
If you own a 3 BR L/O unit then I think it is not a problem as I don't believe there are properties with dedicated 3BR units.