Palm Desert
Thank you, is New Port Coast also in the same general area or I believe it might be close to L.A.
Newport Coast is closer to Los Angeles. It is located in Orange Co and is about 2 hours from Palm Desert. Its also about 10 miles from Santa Ana/John Wayne airport.
As far as airports go here is approximately how far each is from Palm Desert
Palm Springs - your there but this will be the most expensive, few flights
Ontario - about 50 miles (50 minutes) (probably the 2nd least expensive)
Santa Ana/John Wayne - 110 miles (2 hours)
San Diego 120 miles (2.25 hours)
LAX - 140 miles - (2.5 HOURS) this probably the least expensive (3 hours)
These are all approximate estimates assuming no traffic. The day and time of your drive will be a big factor in how long they take. They are all doable.
HOpe this helps