So exactly where do you suggest unpacking, and packing, in a resort or hotel room?
Bathroom sink or tub to hold your suitcase.
Use the metal luggage rack to HOLD your luggage and hang up your clothes. Or turn the plastic trashcan upside down as a luggage rack. Hang pocketbooks up.
Do not throw clothes on the beds or floor ... hang everything UP. Keep the towels off the rugs & soft furniture.
A smart guest strips the bed first, checks under the sofa & chair cushions and around the drapes's seams near heat vents or sunlight hits. If all looks fine, just keep stuff from hitting the floor. I tend to strip the bedspread totally off the bed and throw it into a fall off corner.
I tend to NOT put any of my clothes in the dresser. I hang my pocketbook off a metal/plastic hanger. I leave my clean clothes in the suitcase (held off the floor as suggested above) and the used/dirty clothing goes into a plastic (for the laundry) bag.
I personally first got attacked with bedbugs in Canada in 1976 (Quebec). A college girl friend and I had driven up for a 3 night stay. Riding back home in my car in upper NY state, I notice both of us were scratching our heads, esp around our ears. I pull the car off the highway, opened the truck, opened my suitcase, and SAW little dark round bugs crawling around inside our bags. Without any other prior knowledge, I thought BED BUGS. We continued driving to my house, brought bug spray listed as killing bed bugs, went to the laundry mat, sprayed the car, ourselves, our luggage, showered, changed into clean clothes and REPEATED all again.
I swear we had fathom itching for days ... but saw no more critters. Got no more red welts behind our ears.